Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210497 | 0.85 | SLC6A3 (0.40) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL9215403 | 0.79 | TDP1 (0.36) | SLC6A3HPRT1 | |
| SCHEMBL9699426 | 0.79 | SLC6A4 (0.40) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL9195253 | 0.78 | SLC6A3 (0.38) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL9214501 | 0.77 | KDM4E (0.33) | SLC6A3 | |
| SCHEMBL9701779 | 0.71 | NPC1 (0.34) | — | |
| SCHEMBL6362219 | 0.70 | SLC6A3 (0.40) | SLC6A3SLC6A4 | |
| SCHEMBL6362220 | 0.70 | SLC6A3 (0.40) | SLC6A3SLC6A4 | |
| SCHEMBL9700348 | 0.69 | CES1 (0.36) | SLC6A3 | |
| SCHEMBL9211283 | 0.69 | NPC1 (0.35) | SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992015310-A1 | USE OF TRICYCLIC ISOINDOLINONES AS ANTIVIRAL DRUGS, AND NEW, OPTICALLY ACTIVE ISOINDOLINONES | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-17 | — | — | WO | disclosed |