Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | KRAS | P01116 | 1/20 | 0.55 |
| ▸ | AKR1A1 | P14550 | 3/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27691201 | 0.90 | KMT2A (0.56) | KMT2AHDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL1520240 | 0.85 | TBXAS1 (0.64) | KMT2AALDH1A1TBXAS1STAT3ALOX5 | |
| SCHEMBL18180209 | 0.84 | CDC25A (0.63) | KMT2AALDH1A1TBXAS1STAT3KDM4E | |
| SCHEMBL12874520 | 0.84 | KMT2A (0.66) | KMT2AALDH1A1TBXAS1STAT3ALOX5 | |
| SCHEMBL421164 | 0.83 | KMT2A (0.52) | KMT2AALDH1A1TBXAS1ALOX5AKR1A1 | |
| SCHEMBL6567317 | 0.83 | ALDH1A1 (0.58) | KMT2AHTR6ALDH1A1TBXAS1STAT3 | |
| SCHEMBL8021536 | 0.81 | MCL1 (0.60) | KMT2AHTR6ALDH1A1TBXAS1STAT3 | |
| SCHEMBL27915317 | 0.81 | CNR2 (0.51) | KMT2AHDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL27711191 | 0.81 | TP53 (0.57) | KMT2AALDH1A1STAT3KDM4EAKR1A1 | |
| SCHEMBL27691209 | 0.81 | KMT2A (0.50) | KMT2AHDAC1HDAC8HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132319-A | Antiasthmatic, antiinflammatory, antiallergen and cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1992-07-21 | — | — | US | disclosed |