Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | GLA | P06280 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | GALR3 | O60755 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4474609 | 0.96 | MDM2 (0.62) | MDM2KDM4EALDH1A1GAAGLA | |
| SCHEMBL11737297 | 0.83 | ERCC1 (0.57) | MDM2KDM4EALDH1A1GAAGLA | |
| SCHEMBL11008749 | 0.83 | MCL1 (0.51) | MDM2KDM4EALDH1A1GAAGLA | |
| SCHEMBL7365683 | 0.83 | KDM4E (0.51) | MDM2KDM4EALDH1A1GAAGLA | |
| SCHEMBL11738299 | 0.82 | MDM2 (0.47) | MDM2KDM4EALDH1A1GAAGLA | |
| SCHEMBL9536812 | 0.81 | ALDH1A1 (0.60) | MDM2KDM4EALDH1A1GAAGLA | |
| SCHEMBL3673913 | 0.80 | ATM (0.53) | MDM2KDM4EALDH1A1GAAGLA | |
| SCHEMBL9701560 | 0.79 | KDM4E (0.59) | MDM2KDM4EALDH1A1GAAGLA | |
| SCHEMBL10985180 | 0.79 | KDM4E (0.55) | MDM2KDM4EALDH1A1GAAGLA | |
| SCHEMBL11736292 | 0.79 | KDM4E (0.51) | MDM2KDM4EALDH1A1GAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |