SCHEMBL9701604

SCHEMBL9701604

O=C(O)CC(F)(F)[C](F)Cl

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ACLY P53396 2/20 0.39
ALDH1A1 P00352 1/20 0.36
HMGCR P04035 1/20 0.36
CHRM1 P11229 1/20 0.36
TBXA2R P21731 1/20 0.36
ADRA1A P35348 1/20 0.36
TSHR P16473 2/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
MIF P14174 1/20 0.31
KDM4E B2RXH2 1/20 0.31
FFAR1 O14842 1/20 0.31
CPT2 P23786 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2069147 0.75 ACLY (0.50) ACLYALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL10386312 0.74 ACLY (0.39) ACLYALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL28471080 0.72 ACLY (0.48) ACLYALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL4654792 0.70 ACLY (0.41) ACLYALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL3751513 0.69
SCHEMBL3751363 0.69
SCHEMBL25288451 0.68 ACLY (0.39) ACLYALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL9438232 0.67 ACLY (0.48) ACLYALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL25772273 0.67 ACLY (0.48) ACLYALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL185832 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992006135-A1 CATIONIC LAMINAR COMPOUNDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1992-04-16 WO disclosed