Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HMGCR | P04035 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.39 |
| ▸ | CPT2 | P23786 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28471080 | 0.97 | ACLY (0.48) | ACLYALDH1A1CYP2D6TSHRCYP2C19 | |
| SCHEMBL21411497 | 0.78 | TSHR (0.38) | ACLYALDH1A1CYP2D6TSHRCYP2C19 | |
| SCHEMBL18265069 | 0.77 | TSHR (0.36) | ACLYALDH1A1CYP2D6TSHRCYP2C19 | |
| SCHEMBL4654792 | 0.77 | ACLY (0.41) | ACLYALDH1A1CYP2D6TSHRCYP2C19 | |
| SCHEMBL2647027 | 0.76 | HMGCR (0.39) | ACLYALDH1A1CYP2D6TSHRCYP2C19 | |
| SCHEMBL32659785 | 0.75 | ACLY (0.50) | ACLYALDH1A1CYP2D6TSHRCYP2C19 | |
| SCHEMBL25288451 | 0.75 | ACLY (0.39) | ACLYALDH1A1CYP2D6TSHRCYP2C19 | |
| SCHEMBL10386312 | 0.75 | ACLY (0.39) | ACLYALDH1A1CYP2D6TSHRCYP2C19 | |
| SCHEMBL9701604 | 0.75 | ACLY (0.39) | ACLYALDH1A1CYP2D6TSHRCYP2C19 | |
| SCHEMBL14135896 | 0.73 | ALDH1A1 (0.36) | ACLYALDH1A1CYP2D6TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120056566-A | High-light-transmittance flexible barrier film and preparation method thereof | 江苏思尔德科技有限公司 | 2025-05-30 | — | — | CN | claimed |
| US-20240299325-A1 | SUCCINIC ACID AND DERIVATIVES FOR THE TREATMENT OF HAEMOTOLOGICAL DISORDERS | ENZENE BIOSCIENCES LIMITED (IN) | 2024-09-12 | — | — | US | claimed |
| CN-115873239-B | Preparation method of copolymerization modified PA10T and modified PA10T copolymer thereof | 川化集团有限责任公司 | 2024-07-05 | — | — | CN | claimed |
| CN-115873239-A | Preparation method of copolymerization modified PA10T and modified PA10T copolymer thereof | 川化集团有限责任公司 | 2023-03-31 | — | — | CN | claimed |
| EP-3810121-A1 | SUCCINIC ACID AND DERIVATIVES FOR THE TREATMENT OF HAEMOTOLOGICAL DISORDERS | Enzene Biosciences Ltd. (IN) | 2021-04-28 | — | — | EP | claimed |
| CN-112292123-A | Succinic acid and derivatives for the treatment of hematological disorders | 恩泽生物科学有限公司 | 2021-01-29 | — | — | CN | claimed |
| WO-2019244133-A1 | SUCCINIC ACID AND DERIVATIVES FOR THE TREATMENT OF HAEMOTOLOGICAL DISORDERS | ENZENE BIOSCIENCES LIMITED (IN) | 2019-12-26 | — | — | WO | claimed |
| US-5908768-A | EFFICIENT BIOSYNTHESIS | AJINOMOTO CO., INC. (JP) | 1999-06-01 | — | — | US | claimed |
| US-4169763-A | OF A CORYNEBACTERIA RESISTANT TO ASPARTIC ACID ANALOGS AND SULFA DRUGS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1979-10-02 | — | — | US | claimed |
| JP-62091194-A | — | — | None | — | — | JP | disclosed |
| US-12391664-B2 | GluN2C/D subunit selective antagonists of the N-methyl-D-aspartate receptor | EMORY UNIVERSITY (US) | 2025-08-19 | — | — | US | disclosed |
| US-12344597-B2 | Alkoxy-substituted pyridinyl derivatives as LPA1 receptor antagonists and their use in the treatment of fibrosis | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-07-01 | — | — | US | disclosed |
| CN-120056566-A | High-light-transmittance flexible barrier film and preparation method thereof | 江苏思尔德科技有限公司 | 2025-05-30 | — | — | CN | disclosed |
| US-20240299325-A1 | SUCCINIC ACID AND DERIVATIVES FOR THE TREATMENT OF HAEMOTOLOGICAL DISORDERS | ENZENE BIOSCIENCES LIMITED (IN) | 2024-09-12 | — | — | US | disclosed |
| EP-0213536-A2 | Process for producing L-threonine by fermentation | TORAY INDUSTRIES, INC. (JP) | 1987-03-11 | — | — | EP | disclosed |
| US-4599330-A | 24,24-DIFLUORO-1,25-DIHYDROXYCHOLECALCIFEROL | HOFFMANN-LA ROCHE INC. (US) | 1986-07-08 | — | — | US | disclosed |
| US-4421690-A | ANTI-RACHITOGENIC | HOFFMANN-LA ROCHE INC. (US) | 1983-12-20 | — | — | US | disclosed |
| US-4397847-A | OF OSTEOPOROSIS WITH 24,24-DIFLUORO-1,25-DIHYDROXYCHOLECALCIFEROL | HOFFMANN-LA ROCHE INC. (US) | 1983-08-09 | — | — | US | disclosed |
| US-4169763-A | OF A CORYNEBACTERIA RESISTANT TO ASPARTIC ACID ANALOGS AND SULFA DRUGS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1979-10-02 | — | — | US | disclosed |
| JP-S06291194-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12344597-B2 | Alkoxy-substituted pyridinyl derivatives as LPA1 receptor antagonists and their use in the treatment of fibrosis | LPAR1, LPAR3, LPAR2 | ACLY 2202/4885ALDH1A1 452/4885CYP2D6 2056/4885 |
| US-12391664-B2 | GluN2C/D subunit selective antagonists of the N-methyl-D-aspartate receptor | GRIN2C, GRIN2A, GRIN2B | ACLY 2860/4885ALDH1A1 1930/4885CYP2D6 3492/4885 |
| US-20240299325-A1 | SUCCINIC ACID AND DERIVATIVES FOR THE TREATMENT OF HAEMOTOLOGICAL DISORDERS | STIP1, SORD, DLST | ACLY 99/4885ALDH1A1 151/4885CYP2D6 610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.