Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UNG | P13051 | 5/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | PLK1 | P53350 | 2/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | TACR2 | P21452 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL501783 | 0.83 | CNR2 (0.45) | — | |
| SCHEMBL19985672 | 0.80 | HPGD (0.44) | PLK1ALDH1A1LMNATP53HSD17B10 | |
| SCHEMBL502051 | 0.80 | AKR1C3 (0.48) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL7652240 | 0.77 | HPGD (0.50) | PLK1ALDH1A1LMNAKCNH2 | |
| SCHEMBL28534367 | 0.76 | KCNH2 (0.61) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL28525880 | 0.76 | KCNH2 (0.61) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL12605603 | 0.75 | PLK1 (0.44) | UNGSPHK1PLK1ESR1ADRA2A | |
| SCHEMBL502028 | 0.75 | CNR2 (0.42) | — | |
| SCHEMBL60134 | 0.74 | ESR1 (0.61) | UNGSPHK1ESR1ADRA2AADORA3 | |
| SCHEMBL9330410 | 0.74 | ESR1 (0.61) | UNGSPHK1ESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091099-A | Phosphite-free; containing aromatic amines and substituted phenols | CIBA-GEIGY CORPORATION (US) | 1992-02-25 | — | — | US | disclosed |