Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701641 | 1.00 | LMNA (0.47) | LMNAALDH1A1GAAKMT2AHRH3 | |
| SCHEMBL9702497 | 0.86 | LMNA (0.52) | LMNAALDH1A1GAAKMT2AHRH3 | |
| SCHEMBL9702502 | 0.86 | LMNA (0.52) | LMNAALDH1A1GAAKMT2AHRH3 | |
| SCHEMBL1237539 | 0.84 | LMNA (0.55) | LMNAALDH1A1GAAKMT2AHRH3 | |
| SCHEMBL1804892 | 0.84 | LMNA (0.55) | LMNAALDH1A1GAAKMT2AHRH3 | |
| SCHEMBL7265568 | 0.75 | HPGD (0.52) | LMNAALDH1A1KMT2ANPC1HPGD | |
| SCHEMBL7289930 | 0.75 | LMNA (0.55) | LMNAALDH1A1KMT2AHRH3NPC1 | |
| SCHEMBL29416795 | 0.75 | LMNA (0.55) | LMNAHRH3NPC1RAB9APOLB | |
| SCHEMBL7267256 | 0.75 | HRH3 (0.53) | LMNAALDH1A1GAAKMT2AHRH3 | |
| SCHEMBL7267106 | 0.74 | TP53 (0.59) | LMNAALDH1A1TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118811-A | Treatment and prevention of dementia and amnesia | JAPAN TOBACCO INC. (JP) | 1992-06-02 | — | — | US | claimed |
| EP-0419683-A1 | NEW AMINO ACID DERIVATIVES HAVING PROLYLENDOPEPTIDASE INHIBITOR ACTIVITY | Japan Tobacco Inc. (JP) | 1991-04-03 | — | — | EP | claimed |
| US-5118811-A | Treatment and prevention of dementia and amnesia | JAPAN TOBACCO INC. (JP) | 1992-06-02 | — | — | US | disclosed |