Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5924185 | 0.85 | CA12 (0.55) | TSHRALDH1A1NPC1USP2RAB9A | |
| SCHEMBL11232547 | 0.81 | GPR35 (0.46) | GPR35TSHRALDH1A1NPC1JMJD6 | |
| SCHEMBL10860803 | 0.81 | GPR35 (0.48) | GPR35TSHRALDH1A1JMJD6CA12 | |
| SCHEMBL559800 | 0.80 | GPR35 (0.53) | GPR35TSHRALDH1A1NPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL28235464 | 0.78 | GPR35 (0.52) | GPR35TSHRALDH1A1NPC1RAB9A | |
| SCHEMBL6580266 | 0.78 | ALDH1A1 (0.59) | GPR35TSHRALDH1A1JMJD6CA12 | |
| SCHEMBL11232540 | 0.78 | GPR35 (0.43) | GPR35TSHRALDH1A1NPC1JMJD6 | |
| SCHEMBL11586956 | 0.77 | GPR35 (0.43) | GPR35TSHRALDH1A1NPC1JMJD6 | |
| SCHEMBL3864388 | 0.77 | ALDH1A1 (0.50) | GPR35TSHRALDH1A1NPC1JMJD6 | |
| SCHEMBL4503546 | 0.76 | ALDH1A1 (0.50) | TSHRALDH1A1HSD17B10JMJD6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106943-A | Molding materials; blend of trimer of polyisocyanate, epoxy compounds, and aromatic polyamine | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-21 | — | — | US | disclosed |
| EP-0421393-A2 | Resin, compositions, shaped articles, and methods for manufacture | Takeda Chemical Industries, Ltd. (JP) | 1991-04-10 | — | — | EP | disclosed |