Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 11/20 | 0.67 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702352 | 0.87 | PREP (0.65) | PREPDPP4CTRB1 | |
| SCHEMBL9701705 | 0.87 | PREP (0.65) | PREPDPP4CTRB1 | |
| SCHEMBL5711239 | 0.85 | PREP (0.72) | PREPCTRB1NPSR1 | |
| SCHEMBL8998438 | 0.81 | PREP (0.69) | PREPCTRB1NPSR1 | |
| SCHEMBL9704488 | 0.81 | PREP (0.66) | PREPCTRB1NPSR1 | |
| SCHEMBL8998429 | 0.81 | PREP (0.69) | PREPCTRB1NPSR1 | |
| SCHEMBL9704492 | 0.81 | PREP (0.66) | PREPCTRB1NPSR1 | |
| SCHEMBL9701698 | 0.80 | DPP4 (0.48) | PREPDPP4 | |
| SCHEMBL1437422 | 0.80 | PREP (0.69) | PREPDPP4 | |
| SCHEMBL1437419 | 0.80 | PREP (0.69) | PREPDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118811-A | Treatment and prevention of dementia and amnesia | JAPAN TOBACCO INC. (JP) | 1992-06-02 | — | — | US | claimed |
| EP-0419683-A1 | NEW AMINO ACID DERIVATIVES HAVING PROLYLENDOPEPTIDASE INHIBITOR ACTIVITY | Japan Tobacco Inc. (JP) | 1991-04-03 | — | — | EP | claimed |
| US-5118811-A | Treatment and prevention of dementia and amnesia | JAPAN TOBACCO INC. (JP) | 1992-06-02 | — | — | US | disclosed |
| EP-0419683-A1 | NEW AMINO ACID DERIVATIVES HAVING PROLYLENDOPEPTIDASE INHIBITOR ACTIVITY | Japan Tobacco Inc. (JP) | 1991-04-03 | — | — | EP | disclosed |