Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700902 | 0.77 | POLB (0.36) | HTTPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL12258324 | 0.75 | CHKA (0.47) | CHKAHTTNR3C2DHFRALDH1A1 | |
| SCHEMBL7615550 | 0.72 | POLB (0.44) | HTTPOLBDHFRALDH1A1CYP3A4 | |
| SCHEMBL20385081 | 0.72 | MEN1 (0.52) | CHKAHTTNR3C2ALDH1A1MEN1 | |
| Benzene SCHEMBL14537401 | 0.72 | MEN1 (0.52) | CHKAHTTNR3C2ALDH1A1MEN1 | |
| SCHEMBL6567354 | 0.72 | MEN1 (0.52) | CHKAHTTNR3C2ALDH1A1MEN1 | |
| SCHEMBL31886 | 0.72 | MEN1 (0.52) | CHKAHTTNR3C2ALDH1A1MEN1 | |
| SCHEMBL22931682 | 0.72 | MEN1 (0.52) | CHKAHTTNR3C2ALDH1A1MEN1 | |
| SCHEMBL11700167 | 0.71 | MEN1 (0.40) | CHKAHTTNR3C2ALDH1A1MEN1 | |
| Alcohol SCHEMBL11357181 | 0.71 | CHKA (0.48) | CHKAHTTNR3C2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114975-A | Insecticides and miticides | CIBA-GEIGY CORPORATION (US) | 1992-05-19 | — | — | US | disclosed |
| EP-0304402-B1 | ANILINOPHENYL THIOUREAS, ISOTHIOUREAS AND CARBODIIMIDES, THEIR PREPARATION AND THEIR USE IN PEST-CONTROL | CIBA-GEIGY AG (CH) | 1992-05-06 | — | — | EP | disclosed |
| US-5026730-A | Anilinophenylthioureas, compositions containing them, and the use thereof in pest control | CIBA-GEIGY CORPORATION (US) | 1991-06-25 | — | — | US | disclosed |
| EP-0304402-A2 | Anilinophenyl thioureas, isothioureas and carbodiimides, their preparation and their use in pest-control | CIBA-GEIGY AG (CH) | 1989-02-22 | — | — | EP | disclosed |