Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701945 | 0.77 | CHKA (0.39) | POLBHTTALDH1A1MAPTKDM4E | |
| SCHEMBL9700700 | 0.76 | GABRA1 (0.51) | POLBALDH1A1 | |
| SCHEMBL9700883 | 0.75 | GABRA1 (0.32) | — | |
| SCHEMBL5516786 | 0.75 | ALDH1A1 (0.42) | POLBHTTALDH1A1MAPTKDM4E | |
| SCHEMBL43388 | 0.75 | ALDH1A1 (0.42) | POLBHTTALDH1A1MAPTKDM4E | |
| SCHEMBL9700892 | 0.75 | GABRA1 (0.32) | — | |
| SCHEMBL9701957 | 0.74 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL1487730 | 0.73 | TSPO (0.41) | HTTALDH1A1TSHRRAB9AMEN1 | |
| SCHEMBL3725404 | 0.73 | ALDH1A1 (0.42) | POLBHTTALDH1A1TSHRL3MBTL1 | |
| SCHEMBL9699565 | 0.72 | CYP3A4 (0.58) | HTTALDH1A1MAPTKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114975-A | Insecticides and miticides | CIBA-GEIGY CORPORATION (US) | 1992-05-19 | — | — | US | disclosed |
| EP-0304402-B1 | ANILINOPHENYL THIOUREAS, ISOTHIOUREAS AND CARBODIIMIDES, THEIR PREPARATION AND THEIR USE IN PEST-CONTROL | CIBA-GEIGY AG (CH) | 1992-05-06 | — | — | EP | disclosed |
| US-5026730-A | Anilinophenylthioureas, compositions containing them, and the use thereof in pest control | CIBA-GEIGY CORPORATION (US) | 1991-06-25 | — | — | US | disclosed |
| EP-0304402-A2 | Anilinophenyl thioureas, isothioureas and carbodiimides, their preparation and their use in pest-control | CIBA-GEIGY AG (CH) | 1989-02-22 | — | — | EP | disclosed |