Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | TPMT | P51580 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 3/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703287 | 0.77 | CA1 (0.46) | CA1CA2PRSS1ALDH1A1MAPT | |
| SCHEMBL14611953 | 0.77 | MAOB (0.58) | MAOBCYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL9701899 | 0.75 | PARP1 (0.51) | TSHRPRSS1MAPK1PDE4APDE4B | |
| SCHEMBL9701879 | 0.74 | MAPT (0.47) | CYP2C19CYP1A2TSHRCA12CA1 | |
| SCHEMBL9700914 | 0.74 | ALDH1A1 (0.41) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1260548 | 0.74 | TSHR (0.63) | MAOBCYP2C9CYP2C19CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL4512041 | 0.72 | TSHR (0.61) | MAOBCYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL9703267 | 0.72 | CA12 (0.44) | CYP3A4CA12CA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL29112504 | 0.72 | TSHR (0.61) | MAOBCYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL18848298 | 0.72 | CYP2C9 (0.61) | MAOBCYP2C9CYP2C19CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |