Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701621 | 0.88 | ALDH1A1 (0.57) | MAPTHTTADRA1AADRA2AALDH1A1 | |
| SCHEMBL9701649 | 0.79 | CTSD (0.49) | MAPTHTTALDH1A1HPGDTAAR1 | |
| SCHEMBL2205896 | 0.76 | HTT (0.60) | MAPTHTTNPSR1ADRA1AADRA2A | |
| SCHEMBL29584738 | 0.76 | HTT (0.60) | MAPTHTTNPSR1ADRA1AADRA2A | |
| SCHEMBL9703287 | 0.75 | CA1 (0.46) | MAPTALDH1A1CA1CA2 | |
| SCHEMBL9701949 | 0.74 | MAOB (0.54) | MAPTALDH1A1HPGDCA12CA1 | |
| SCHEMBL11110902 | 0.73 | MAPT (0.49) | MAPTHTTNPSR1ADRA1AADRA2A | |
| SCHEMBL9701899 | 0.73 | PARP1 (0.51) | MAPTNPSR1ALDH1A1TAAR1MEN1 | |
| SCHEMBL9701904 | 0.73 | ADRA1A (0.58) | ADRA1AADRA2ATAAR1MEN1KMT2A | |
| SCHEMBL9700886 | 0.72 | CA12 (0.47) | MAPTHTTADRA1AADRA2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |