Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 8/20 | 0.46 |
| ▸ | CASP5 | P51878 | 8/20 | 0.46 |
| ▸ | CASP4 | P49662 | 6/20 | 0.46 |
| ▸ | HTR1A | P08908 | 7/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT5A | Q9NQR1 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702220 | 0.79 | CASP1 (0.53) | CASP1CASP5CASP4HTR1AKMT5A | |
| SCHEMBL9688215 | 0.77 | CASP1 (0.55) | CASP1CASP5CASP4HTR1ADRD2 | |
| SCHEMBL9688140 | 0.74 | CASP1 (0.62) | CASP1CASP5CASP4DRD2HTR2C | |
| SCHEMBL9689097 | 0.74 | CASP1 (0.58) | CASP1CASP5CASP4TLR9TLR7 | |
| SCHEMBL9688138 | 0.74 | CASP1 (0.58) | CASP1CASP5CASP4TLR9TLR7 | |
| Hydrochloric Acid SCHEMBL10367476 | 0.73 | CASP1 (0.61) | CASP1CASP5CASP4HRH4 | |
| Hydrochloric Acid SCHEMBL9688259 | 0.73 | CASP1 (0.56) | CASP1CASP5CASP4TLR9TLR7 | |
| SCHEMBL9712234 | 0.72 | CASP1 (0.51) | CASP1CASP5CASP4HTR1ADRD2 | |
| SCHEMBL9130732 | 0.72 | CASP1 (0.56) | CASP1CASP5CASP4DRD2HTR2C | |
| SCHEMBL9755203 | 0.71 | CASP1 (0.49) | CASP1CASP5CASP4HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120843-A | Nervous system disorders | UPJOHN (US) | 1992-06-09 | — | — | US | disclosed |