Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.63 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.63 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.63 |
| ▸ | PREP | P48147 | 3/20 | 0.58 |
| ▸ | FAP | Q12884 | 1/20 | 0.55 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29416795 | 0.82 | LMNA (0.55) | LMNA | |
| SCHEMBL1804892 | 0.82 | LMNA (0.55) | DPP4DPP8DPP7LMNA | |
| SCHEMBL7289930 | 0.82 | LMNA (0.55) | LMNA | |
| SCHEMBL1237539 | 0.82 | LMNA (0.55) | DPP4DPP8DPP7LMNA | |
| SCHEMBL26098916 | 0.80 | PREP (0.53) | DPP4DPP8DPP7PREPFAP | |
| SCHEMBL26099593 | 0.79 | DPP4 (0.54) | DPP4DPP8DPP7PREPFAP | |
| SCHEMBL7291612 | 0.78 | LMNA (0.52) | DPP4DPP8DPP7LMNA | |
| SCHEMBL9702497 | 0.78 | LMNA (0.52) | LMNA | |
| SCHEMBL9702502 | 0.78 | LMNA (0.52) | LMNA | |
| SCHEMBL3556999 | 0.78 | DPP4 (1.00) | DPP4DPP8DPP7PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118811-A | Treatment and prevention of dementia and amnesia | JAPAN TOBACCO INC. (JP) | 1992-06-02 | — | — | US | claimed |
| EP-0419683-A1 | NEW AMINO ACID DERIVATIVES HAVING PROLYLENDOPEPTIDASE INHIBITOR ACTIVITY | Japan Tobacco Inc. (JP) | 1991-04-03 | — | — | EP | claimed |
| US-5118811-A | Treatment and prevention of dementia and amnesia | JAPAN TOBACCO INC. (JP) | 1992-06-02 | — | — | US | disclosed |
| EP-0419683-A1 | NEW AMINO ACID DERIVATIVES HAVING PROLYLENDOPEPTIDASE INHIBITOR ACTIVITY | Japan Tobacco Inc. (JP) | 1991-04-03 | — | — | EP | disclosed |