Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.54 |
| ▸ | FAP | Q12884 | 1/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.54 |
| ▸ | PREP | P48147 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26098916 | 0.88 | PREP (0.53) | DPP4DPP7DPP8FAPDPP9 | |
| SCHEMBL26103558 | 0.86 | DPP4 (0.58) | DPP4DPP7DPP8FAPDPP9 | |
| SCHEMBL26097901 | 0.86 | DPP4 (0.58) | DPP4DPP7DPP8FAPDPP9 | |
| SCHEMBL26103379 | 0.82 | HPGD (0.52) | HPGD | |
| SCHEMBL26103078 | 0.80 | HPGD (0.52) | HPGD | |
| SCHEMBL9702382 | 0.79 | DPP4 (0.63) | DPP4DPP7DPP8FAPDPP9 | |
| SCHEMBL26099055 | 0.79 | ROCK2 (0.53) | HPGD | |
| SCHEMBL26102746 | 0.77 | HPGD (0.48) | DPP4HPGD | |
| SCHEMBL26103046 | 0.77 | HPGD (0.48) | DPP4HPGD | |
| SCHEMBL26099857 | 0.76 | MAPT (0.53) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230133132-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133132-A1 | NAMPT MODULATORS | NAMPT, MC4R, SIRT1 | DPP4 2782/4885DPP7 3067/4885DPP8 3205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.