Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854642 | 0.89 | ESR1 (0.59) | ESR1ESR2CYP2D6DRD2DRD4 | |
| SCHEMBL4014770 | 0.80 | DRD2 (0.65) | CYP2D6DRD2DRD4OPRM1DRD3 | |
| SCHEMBL10390700 | 0.79 | ESR1 (0.64) | ESR1ESR2ARCYP3A4LMNA | |
| SCHEMBL10389824 | 0.78 | ESR1 (0.53) | ESR1ESR2ARCYP3A4LMNA | |
| SCHEMBL22085882 | 0.75 | ESR1 (0.44) | ESR1ESR2CCR1 | |
| SCHEMBL10389814 | 0.73 | ESR1 (0.60) | ESR1ESR2ARCYP3A4LMNA | |
| SCHEMBL272801 | 0.73 | ESR1 (1.00) | ESR1ESR2ARCYP3A4LMNA | |
| SCHEMBL673356 | 0.73 | ESR1 (0.68) | ESR1ESR2ARCYP3A4LMNA | |
| SCHEMBL10389822 | 0.72 | ESR1 (0.54) | ESR1ESR2ARCYP3A4LMNA | |
| SCHEMBL69106 | 0.71 | ESR1 (0.65) | ESR1ESR2ARCYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110897-A | Food and beverage containers | GENERAL ELECTRIC COMPANY (US) | 1992-05-05 | — | — | US | disclosed |