Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 6/20 | 0.64 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702643 | 1.00 | PREP (0.64) | PREPCTSKGFERNPSR1MEN1 | |
| SCHEMBL9702301 | 0.90 | PREP (0.59) | PREPCTSKGFERNPSR1MEN1 | |
| SCHEMBL9702297 | 0.90 | PREP (0.59) | PREPCTSKGFERNPSR1MEN1 | |
| SCHEMBL9704488 | 0.88 | PREP (0.66) | PREPGFERNPSR1MEN1KMT2A | |
| SCHEMBL9704492 | 0.88 | PREP (0.66) | PREPGFERNPSR1MEN1KMT2A | |
| SCHEMBL9702413 | 0.83 | PREP (0.45) | PREP | |
| SCHEMBL5711239 | 0.81 | PREP (0.72) | PREPGFERNPSR1KMT2ATSHR | |
| SCHEMBL9703312 | 0.79 | PREP (0.60) | PREPGFERNPSR1MEN1KMT2A | |
| SCHEMBL9703304 | 0.79 | PREP (0.60) | PREPGFERNPSR1MEN1KMT2A | |
| SCHEMBL9701702 | 0.78 | PREP (0.67) | PREPNPSR1CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118811-A | Treatment and prevention of dementia and amnesia | JAPAN TOBACCO INC. (JP) | 1992-06-02 | — | — | US | claimed |
| EP-0419683-A1 | NEW AMINO ACID DERIVATIVES HAVING PROLYLENDOPEPTIDASE INHIBITOR ACTIVITY | Japan Tobacco Inc. (JP) | 1991-04-03 | — | — | EP | claimed |
| US-5118811-A | Treatment and prevention of dementia and amnesia | JAPAN TOBACCO INC. (JP) | 1992-06-02 | — | — | US | disclosed |