Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 12/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9701593 | 0.97 | CA12 (0.35) | CA12CA2CA3CA4CA6 | |
| SCHEMBL9700392 | 0.85 | ALDH1A1 (0.39) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL1934253 | 0.83 | CA12 (0.40) | CA12CA2CA3CA4CA6 | |
| SCHEMBL9701553 | 0.78 | MCHR1 (0.35) | MAPTCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL51563 | 0.77 | EPHX2 (0.30) | EPHX2 | |
| Formic Acid SCHEMBL27230851 | 0.75 | CA12 (0.33) | CA12CA2CA3CA4CA6 | |
| SCHEMBL7729369 | 0.75 | CA12 (0.33) | CA12CA2CA3CA4CA6 | |
| SCHEMBL3763074 | 0.74 | NPC1 (0.36) | CA12CA9CHRM2PHF8KDM2A | |
| Acetic Acid SCHEMBL5526730 | 0.74 | FFAR3 (0.50) | CA12CA2CA3CA4CA6 | |
| Acetic Acid SCHEMBL27684197 | 0.74 | FFAR3 (0.50) | CA12CA2CA3CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132454-A | Antihypoxic agents | MEIJI SEIKA KAISHA, LTD. (JP) | 1992-07-21 | — | — | US | disclosed |
| US-5066677-A | Antihypoxic agents, treatment of disorders resulting from reduced oxygen supply to brain | MEIJI SEIKA KAISHA, LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0387074-A2 | Novel oxamic acid compounds and pharmaceutical composition for use in improvement of damaged cerebral functions of brain | MEIJI SEIKA KAISHA LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |