Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 12/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702710 | 0.85 | CA12 (0.36) | ALDH1A1TSHRKDM4AKDM4CKDM5A | |
| SCHEMBL1934062 | 0.85 | ALDH1A1 (0.43) | ALDH1A1TSHRKDM4AKDM4CKDM5A | |
| Hydrochloric Acid SCHEMBL9701593 | 0.83 | CA12 (0.35) | ALDH1A1KDM4AKDM4CKDM5AKDM7A | |
| SCHEMBL9701275 | 0.80 | BCHE (0.40) | ALDH1A1KDM4CKDM5ASMN1; SMN2EPHX2 | |
| SCHEMBL25330808 | 0.78 | ALDH1A1 (0.55) | ALDH1A1TSHRKDM4AKDM4CKDM5A | |
| SCHEMBL2498409 | 0.77 | PAOX (0.36) | ALDH1A1TSHRKDM4AKDM4CKDM5A | |
| SCHEMBL28903229 | 0.76 | NOS3 (0.38) | ALDH1A1EPHX2 | |
| Hydrochloric Acid SCHEMBL10795220 | 0.76 | PAOX (0.35) | ALDH1A1TSHRKDM4AKDM4CKDM5A | |
| SCHEMBL11240727 | 0.75 | CHRM1 (0.44) | ALDH1A1TSHRKDM4AKDM4CKDM5A | |
| SCHEMBL3932905 | 0.73 | ALDH1A1 (0.41) | ALDH1A1TSHRKDM4AKDM4CKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132454-A | Antihypoxic agents | MEIJI SEIKA KAISHA, LTD. (JP) | 1992-07-21 | — | — | US | disclosed |
| US-5066677-A | Antihypoxic agents, treatment of disorders resulting from reduced oxygen supply to brain | MEIJI SEIKA KAISHA, LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0387074-A2 | Novel oxamic acid compounds and pharmaceutical composition for use in improvement of damaged cerebral functions of brain | MEIJI SEIKA KAISHA LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |