Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 12/20 | 0.74 |
| ▸ | HPRT1 | P00492 | 7/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | POLA1 | P09884 | 1/20 | 0.63 |
| ▸ | POLG | P54098 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905164 | 0.92 | HPRT1 (0.72) | PNPHPRT1POLBPOLA1POLG | |
| SCHEMBL8905172 | 0.91 | HPRT1 (0.71) | PNPHPRT1POLBPOLA1POLG | |
| SCHEMBL9053832 | 0.89 | HPRT1 (0.74) | PNPHPRT1POLBPOLA1POLG | |
| SCHEMBL9701538 | 0.85 | PNP (1.00) | PNPHPRT1 | |
| Gs-438 SCHEMBL64567 | 0.85 | POLB (0.80) | PNPHPRT1POLBPOLA1POLG | |
| SCHEMBL9701491 | 0.84 | PNP (1.00) | PNPHPRT1 | |
| SCHEMBL9702665 | 0.84 | PNP (1.00) | PNPHPRT1 | |
| SCHEMBL973086 | 0.84 | PNP (1.00) | PNPHPRT1 | |
| SCHEMBL8905193 | 0.84 | HPRT1 (0.69) | PNPHPRT1POLBPOLA1POLG | |
| SCHEMBL15078157 | 0.84 | POLB (0.89) | PNPHPRT1POLBPOLA1POLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478292-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-01 | — | — | EP | disclosed |