Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 13/20 | 1.00 |
| ▸ | HPRT1 | P00492 | 7/20 | 0.83 |
| ▸ | TK1 | P04183 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL973086 | 1.00 | PNP (1.00) | PNPHPRT1TK1 | |
| SCHEMBL9702665 | 1.00 | PNP (1.00) | PNPHPRT1TK1 | |
| SCHEMBL9701538 | 0.99 | PNP (1.00) | PNPHPRT1TK1 | |
| SCHEMBL9515948 | 0.91 | PNP (1.00) | PNPHPRT1TK1 | |
| SCHEMBL9702722 | 0.84 | PNP (0.74) | PNPHPRT1 | |
| SCHEMBL9702718 | 0.83 | PNP (0.76) | PNPHPRT1TK1 | |
| SCHEMBL6397381 | 0.83 | PNP (0.76) | PNPHPRT1TK1 | |
| SCHEMBL8175624 | 0.81 | TK1 (0.97) | PNPHPRT1TK1 | |
| SCHEMBL9053832 | 0.80 | HPRT1 (0.74) | PNPHPRT1 | |
| SCHEMBL24940649 | 0.80 | PNP (0.80) | PNPHPRT1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478292-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-01 | — | — | EP | claimed |
| EP-0478292-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-01 | — | — | EP | disclosed |