Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 8/20 | 0.74 |
| ▸ | PNP | P00491 | 11/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | POLA1 | P09884 | 1/20 | 0.67 |
| ▸ | POLG | P54098 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905164 | 0.97 | HPRT1 (0.72) | HPRT1PNPPOLBPOLA1POLG | |
| SCHEMBL8905172 | 0.96 | HPRT1 (0.71) | HPRT1PNPPOLBPOLA1POLG | |
| Gs-438 SCHEMBL64567 | 0.92 | POLB (0.80) | HPRT1PNPPOLBPOLA1POLG | |
| SCHEMBL9702722 | 0.89 | PNP (0.74) | HPRT1PNPPOLBPOLA1POLG | |
| Gs-438 SCHEMBL3497651 | 0.88 | POLB (0.84) | HPRT1PNPPOLBPOLA1POLG | |
| SCHEMBL8896276 | 0.87 | HPRT1 (0.81) | HPRT1PNPPOLBPOLA1POLG | |
| SCHEMBL24940649 | 0.87 | PNP (0.80) | HPRT1PNPPOLBPOLA1POLG | |
| SCHEMBL8898386 | 0.86 | HPRT1 (0.80) | HPRT1PNPPOLBPOLA1POLG | |
| SCHEMBL8905193 | 0.85 | HPRT1 (0.69) | HPRT1PNPPOLBPOLA1POLG | |
| SCHEMBL15078157 | 0.85 | POLB (0.89) | HPRT1PNPPOLBPOLA1POLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269947-B2 | Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives | ACAD OF SCIENCE CZECH REPUBLIC (CS) | 1996-10-16 | — | — | EP | claimed |
| EP-0269947-A1 | Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1988-06-08 | — | — | EP | claimed |