Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700915 | 0.81 | ALDH1A1 (0.38) | HTTLMNAALDH1A1KMT2ATAAR1 | |
| SCHEMBL9702758 | 0.80 | HDAC1 (0.38) | MAPTHSD17B10CYP3A4BLMPMP22 | |
| SCHEMBL9701638 | 0.78 | EGFR (0.38) | TAAR1ACHEBACE1CA12CA1 | |
| SCHEMBL9700906 | 0.78 | EGFR (0.43) | MAPTHSD17B10GFERHIF1ACYP3A4 | |
| SCHEMBL9702052 | 0.76 | ALDH1A1 (0.46) | MAPTHSD17B10CYP3A4LMNAALDH1A1 | |
| SCHEMBL9703287 | 0.76 | CA1 (0.46) | MAPTALDH1A1NR1I2SMN1; SMN2CA1 | |
| SCHEMBL9702172 | 0.72 | ALDH1A1 (0.46) | MAPTGFERHTTLMNAALDH1A1 | |
| SCHEMBL9703351 | 0.72 | CA12 (0.42) | GFERLMNAALDH1A1KDM4EPTGS2 | |
| SCHEMBL7039072 | 0.70 | MAPT (0.52) | MAPTHSD17B10GFERHTTGPR55 | |
| SCHEMBL10594203 | 0.69 | MAPT (0.50) | MAPTHSD17B10GFERHTTGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |