Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38664746 | 0.92 | TDP1 (0.62) | TDP1KMT2AMEN1ATMCA12 | |
| SCHEMBL1411297 | 0.92 | TDP1 (0.62) | TDP1KMT2AMEN1ATMCA12 | |
| Phenylhydrazine SCHEMBL1410333 | 0.84 | TDP1 (0.57) | TDP1KMT2AMEN1ATMCA12 | |
| SCHEMBL28372184 | 0.77 | TDP1 (0.65) | TDP1KMT2AMEN1ATMCA12 | |
| SCHEMBL13485778 | 0.77 | TDP1 (0.65) | TDP1KMT2AMEN1ATMCA12 | |
| SCHEMBL13973365 | 0.77 | CA2 (0.57) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL7199438 | 0.76 | ATM (0.65) | TDP1KMT2AMEN1ATMHPGD | |
| SCHEMBL6530771 | 0.76 | TDP1 (0.62) | TDP1KMT2AMEN1ATMCA12 | |
| SCHEMBL11419959 | 0.76 | TDP1 (0.62) | TDP1KMT2AMEN1ATMCA12 | |
| SCHEMBL14504321 | 0.75 | TDP1 (0.57) | TDP1KMT2AMEN1ATMCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992003732-A2 | COMPOSITIONS AND METHODS FOR ENHANCED BINDING IN BIOLOGICAL ASSAYS | BIOPROBE INTERNATIONAL, INC. (US) | 1992-03-05 | — | — | WO | disclosed |