Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13182758 | 0.83 | KMT2A (0.60) | ALDH1A1NPC1RAB9AHPGDHSD17B10 | |
| SCHEMBL9787096 | 0.83 | ALDH1A1 (0.59) | ALDH1A1NPC1RAB9AHPGDHSD17B10 | |
| SCHEMBL28504230 | 0.83 | CA1 (0.62) | ALDH1A1NPC1RAB9AHPGDHSD17B10 | |
| SCHEMBL6826773 | 0.80 | KMT2A (0.60) | ALDH1A1NPC1RAB9AHPGDHSD17B10 | |
| SCHEMBL13006685 | 0.80 | ALDH1A1 (0.60) | ALDH1A1NPC1RAB9AHPGDKDM4E | |
| SCHEMBL9725094 | 0.74 | NPC1 (0.59) | ALDH1A1NPC1RAB9AHPGDHSD17B10 | |
| SCHEMBL2645324 | 0.74 | LTA4H (0.58) | ALDH1A1NPC1RAB9ALTA4HMAPK1 | |
| SCHEMBL11771528 | 0.73 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9AHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL5253545 | 0.72 | LTA4H (0.56) | ALDH1A1NPC1RAB9ALTA4HMAPK1 | |
| SCHEMBL25311154 | 0.72 | HDAC4 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012154-A1 | IMIDAZOTRIAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-23 | — | — | WO | disclosed |