Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | OGG1 | O15527 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 6/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702868 | 1.00 | MAPT (1.00) | MAPTALDH1A1LMNACYP2C9MEN1 | |
| SCHEMBL8290975 | 0.85 | CYP2C9 (1.00) | MAPTALDH1A1LMNACYP2C9MEN1 | |
| SCHEMBL2974814 | 0.84 | CYP2C9 (0.77) | MAPTALDH1A1LMNACYP2C9MEN1 | |
| SCHEMBL9512356 | 0.83 | CYP2C9 (0.75) | MAPTALDH1A1LMNACYP2C9MEN1 | |
| SCHEMBL9512365 | 0.83 | CYP2C9 (0.75) | MAPTALDH1A1LMNACYP2C9MEN1 | |
| SCHEMBL3267992 | 0.83 | CYP2C9 (0.75) | MAPTALDH1A1LMNACYP2C9MEN1 | |
| SCHEMBL17253327 | 0.83 | CYP2C9 (0.75) | MAPTALDH1A1LMNACYP2C9MEN1 | |
| SCHEMBL2770921 | 0.83 | CYP2C9 (0.75) | MAPTALDH1A1LMNACYP2C9MEN1 | |
| SCHEMBL11041282 | 0.82 | ALDH1A1 (0.70) | MAPTALDH1A1LMNACYP2C9MEN1 | |
| SCHEMBL11041289 | 0.82 | ALDH1A1 (0.70) | MAPTALDH1A1LMNACYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143642-A | Thiadiazoles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |