Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702980 | 0.92 | SMN1; SMN2 (0.56) | ALDH1A1KDM4EMAPTTP53HSD17B10 | |
| SCHEMBL9702474 | 0.86 | RAB9A (0.63) | ALDH1A1KDM4EMAPTTP53HSD17B10 | |
| SCHEMBL31413844 | 0.82 | KDM4E (0.58) | ALDH1A1KDM4EMAPTTP53HSD17B10 | |
| SCHEMBL2542170 | 0.82 | KDM4E (0.58) | ALDH1A1KDM4EMAPTTP53HSD17B10 | |
| SCHEMBL9702249 | 0.82 | RAB9A (0.58) | ALDH1A1KDM4EMAPTTP53HSD17B10 | |
| SCHEMBL9704789 | 0.81 | RAB9A (0.47) | ALDH1A1KDM4EMAPTTP53HSD17B10 | |
| SCHEMBL9702829 | 0.81 | RAB9A (0.51) | ALDH1A1KDM4EMAPTTP53HSD17B10 | |
| SCHEMBL1566839 | 0.81 | KDM4E (0.53) | ALDH1A1KDM4EMAPTTP53HSD17B10 | |
| SCHEMBL6663651 | 0.80 | KDM4E (0.75) | ALDH1A1KDM4EMAPTTP53HSD17B10 | |
| SCHEMBL10058752 | 0.80 | QPCTL (0.40) | KDM4EMAPTTP53HSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143642-A | Thiadiazoles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |