Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.63 |
| ▸ | TP53 | P04637 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702249 | 0.96 | RAB9A (0.58) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL9705079 | 0.92 | RAB9A (0.61) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL9704963 | 0.86 | RAB9A (0.55) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL9702907 | 0.86 | ALDH1A1 (0.57) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL9702337 | 0.85 | RAB9A (0.53) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL9704965 | 0.85 | RAB9A (0.60) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL6658682 | 0.83 | RAB9A (0.46) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL6658687 | 0.83 | RAB9A (0.46) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL6657901 | 0.83 | RAB9A (0.46) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL6657907 | 0.83 | RAB9A (0.46) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143642-A | Thiadiazoles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |