Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.54 |
| ▸ | RELA | Q04206 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | STAT1 | P42224 | 1/20 | 0.54 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.54 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702950 | 0.82 | SLC2A1 (0.59) | SLC2A1NPC1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL9599277 | 0.82 | SLC2A1 (0.55) | SLC2A1NPC1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL9379605 | 0.81 | ALDH1A1 (0.57) | NPC1SMN1; SMN2RAB9AALDH1A1PKM | |
| SCHEMBL10699867 | 0.77 | NPC1 (0.58) | SLC2A1NPC1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL8603235 | 0.77 | SLC2A1 (0.76) | SLC2A1NPC1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL419326 | 0.77 | NPC1 (0.71) | SLC2A1NPC1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL30637066 | 0.77 | MMP12 (0.56) | NPC1SMN1; SMN2RAB9AALDH1A1PKM | |
| SCHEMBL558709 | 0.77 | MAPKAPK2 (0.58) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL558123 | 0.77 | MMP12 (0.56) | NPC1SMN1; SMN2RAB9AALDH1A1PKM | |
| SCHEMBL24074302 | 0.76 | ALDH1A1 (0.63) | SLC2A1NPC1SMN1; SMN2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116843-A | Anticoagulants, hypotensive agents and cardiovascular disorder | BOEHRINGER MANNHEIM GMBH (DE) | 1992-05-26 | — | — | US | disclosed |