Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.79 |
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | CRHBP | P24387 | 2/20 | 0.64 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | PLAU | P00749 | 1/20 | 0.62 |
| ▸ | ELANE | P08246 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10793129 | 0.85 | ALDH1A1 (0.65) | ALDH1A1LMNAL3MBTL1HTTCRHBP | |
| SCHEMBL11705060 | 0.84 | MAPT (0.79) | ALDH1A1LMNAL3MBTL1CRHBPCRHR2 | |
| SCHEMBL6770004 | 0.82 | LMNA (0.73) | ALDH1A1LMNAL3MBTL1HTTCRHBP | |
| SCHEMBL10594113 | 0.80 | ALDH1A1 (0.66) | ALDH1A1LMNAL3MBTL1HTTKDM4E | |
| SCHEMBL5673419 | 0.80 | POLB (0.65) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2GAA | |
| SCHEMBL4930749 | 0.78 | ALDH1A1 (0.68) | ALDH1A1LMNAL3MBTL1HTTCRHBP | |
| SCHEMBL19825010 | 0.78 | MAPT (0.65) | ALDH1A1LMNAL3MBTL1HTTCRHBP | |
| SCHEMBL4927732 | 0.78 | GAA (0.75) | ALDH1A1LMNAL3MBTL1HTTKDM4E | |
| SCHEMBL4930245 | 0.78 | MAPT (0.69) | ALDH1A1LMNAL3MBTL1CRHBPCRHR2 | |
| SCHEMBL19899864 | 0.78 | MAPT (0.69) | ALDH1A1LMNAL3MBTL1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143642-A | Thiadiazoles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |