Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CDK4 | P11802 | 4/20 | 0.49 |
| ▸ | CCND1 | P24385 | 4/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24814484 | 0.81 | KMT2A (0.65) | KMT2ANTSR1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL30074152 | 0.78 | KMT2A (0.71) | KMT2ANTSR1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL9701534 | 0.78 | KMT2A (0.71) | KMT2ANTSR1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL6679035 | 0.78 | KMT2A (0.65) | KMT2ANTSR1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL29420405 | 0.76 | KMT2A (1.00) | KMT2ANTSR1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL1598786 | 0.76 | KMT2A (1.00) | KMT2ANTSR1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL1519806 | 0.75 | KMT2A (0.71) | KMT2ANTSR1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL29955957 | 0.75 | KMT2A (0.71) | KMT2ANTSR1MAPK1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL25303352 | 0.75 | KMT2A (0.96) | KMT2ANTSR1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL16286740 | 0.75 | KMT2A (0.71) | KMT2ANTSR1MAPK1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132319-A | Antiasthmatic, antiinflammatory, antiallergen and cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1992-07-21 | — | — | US | disclosed |