Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | CDK4 | P11802 | 4/20 | 0.57 |
| ▸ | CCND1 | P24385 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.55 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701534 | 1.00 | KMT2A (0.71) | KMT2AMAPK1CDK4CCND1LMNA | |
| SCHEMBL27602860 | 0.85 | KMT2A (0.65) | KMT2AMAPK1CDK4CCND1LMNA | |
| SCHEMBL1598786 | 0.83 | KMT2A (1.00) | KMT2AMAPK1CDK4CCND1LMNA | |
| SCHEMBL29420405 | 0.83 | KMT2A (1.00) | KMT2AMAPK1CDK4CCND1LMNA | |
| Acetic Acid SCHEMBL27760597 | 0.83 | KMT2A (0.68) | KMT2AMAPK1CDK4CCND1LMNA | |
| SCHEMBL12881191 | 0.82 | LMNA (0.71) | KMT2AMAPK1CDK4CCND1LMNA | |
| SCHEMBL15262402 | 0.82 | KMT2A (0.66) | KMT2AMAPK1CDK4CCND1LMNA | |
| SCHEMBL15262406 | 0.82 | KMT2A (0.66) | KMT2AMAPK1CDK4CCND1LMNA | |
| Hydrochloric Acid SCHEMBL25303352 | 0.81 | KMT2A (0.96) | KMT2AMAPK1CDK4CCND1LMNA | |
| SCHEMBL1519806 | 0.81 | KMT2A (0.71) | KMT2AMAPK1CDK4CCND1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691959-B2 | Anti-inflammatory and antitumor 2-oxothiazoles and 2-oxothiophenes compounds | AVEXXIN AS (NO) | 2023-07-04 | — | — | US | disclosed |
| US-20220363659-A1 | ANTI-INFLAMMATORY AND ANTITUMOR 2-OXOTHIAZOLES AND 2-OXOTHIOPHENES COMPOUNDS | AVEXXIN AS (NO) | 2022-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220363659-A1 | ANTI-INFLAMMATORY AND ANTITUMOR 2-OXOTHIAZOLES AND 2-OXOTHIOPHENES COMPOUNDS | OXER1, CASP1, IL6 | KMT2A 2837/4885MAPK1 916/4885CDK4 1341/4885 |
| US-11691959-B2 | Anti-inflammatory and antitumor 2-oxothiazoles and 2-oxothiophenes compounds | CASP1, IL1B, OXER1 | KMT2A 3107/4885MAPK1 879/4885CDK4 1660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.