Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | FAAH | O00519 | 4/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507450 | 1.00 | LMNA (0.61) | LMNAACE2MAPTMAPK1FAAH | |
| SCHEMBL9509877 | 1.00 | LMNA (0.61) | LMNAACE2MAPTMAPK1FAAH | |
| SCHEMBL9509850 | 0.98 | LMNA (0.58) | LMNAACE2MAPTMAPK1FAAH | |
| SCHEMBL9509874 | 0.93 | LMNA (0.50) | LMNAACE2MAPTMAPK1FAAH | |
| SCHEMBL27465616 | 0.91 | LMNA (0.71) | LMNAMAPTMAPK1FAAHCNR1 | |
| SCHEMBL9768561 | 0.86 | LMNA (0.69) | LMNAMAPTMAPK1FAAHCNR1 | |
| SCHEMBL18187969 | 0.86 | LMNA (0.69) | LMNAMAPTMAPK1FAAHCNR1 | |
| SCHEMBL8644265 | 0.86 | LMNA (0.69) | LMNAMAPTMAPK1FAAHCNR1 | |
| SCHEMBL8419699 | 0.86 | LMNA (0.69) | LMNAMAPTMAPK1FAAHCNR1 | |
| SCHEMBL22443356 | 0.86 | LMNA (0.69) | LMNAMAPTMAPK1FAAHCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |