Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 4/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509850 | 0.95 | LMNA (0.58) | LMNAACE2FAAHCNR1CNR2 | |
| SCHEMBL9507450 | 0.93 | LMNA (0.61) | LMNAACE2FAAHCNR1CNR2 | |
| SCHEMBL9509877 | 0.93 | LMNA (0.61) | LMNAACE2FAAHCNR1CNR2 | |
| SCHEMBL9703061 | 0.93 | LMNA (0.61) | LMNAACE2FAAHCNR1CNR2 | |
| SCHEMBL9511204 | 0.89 | CYP1A2 (0.47) | LMNAACE2FAAHCNR1CNR2 | |
| SCHEMBL11386694 | 0.85 | LMNA (0.57) | LMNAFAAHCNR1CNR2MAPT | |
| SCHEMBL880135 | 0.85 | LMNA (0.57) | LMNAFAAHCNR1CNR2CYP1A2 | |
| SCHEMBL9508692 | 0.84 | LMNA (0.52) | LMNAFAAHCNR1CNR2MAPT | |
| SCHEMBL27465616 | 0.83 | LMNA (0.71) | LMNAFAAHCNR1CNR2CYP1A2 | |
| SCHEMBL22534407 | 0.83 | FAAH (0.60) | LMNAFAAHCNR1CNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |