Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702851 | 0.91 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1GAAKMT2AHTT | |
| SCHEMBL9703901 | 0.89 | SMN1; SMN2 (0.54) | SMN1; SMN2MEN1GAAKMT2AHTT | |
| SCHEMBL9702695 | 0.89 | ALDH1A1 (0.49) | SMN1; SMN2MEN1GAAKMT2ALMNA | |
| SCHEMBL9703922 | 0.89 | MEN1 (0.49) | SMN1; SMN2MEN1GAAKMT2ALMNA | |
| SCHEMBL9702676 | 0.88 | SMN1; SMN2 (0.48) | SMN1; SMN2MEN1GAAKMT2AHTT | |
| SCHEMBL9704884 | 0.88 | SMN1; SMN2 (0.48) | SMN1; SMN2MEN1GAAKMT2AHTT | |
| SCHEMBL9703137 | 0.87 | KMT2A (0.47) | SMN1; SMN2MEN1GAAKMT2AHTT | |
| SCHEMBL9704867 | 0.87 | KMT2A (0.47) | SMN1; SMN2MEN1GAAKMT2AHTT | |
| SCHEMBL9703141 | 0.87 | KMT2A (0.47) | SMN1; SMN2MEN1GAAKMT2AHTT | |
| SCHEMBL9702660 | 0.86 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1GAAKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738977-A | 2-pyridylacetic acid derivatives, pharmaceutical composition containing the same and their use in treating ulcers | SUNTORY LIMITED (JP) | 1988-04-19 | — | — | US | claimed |
| EP-0223512-B1 | 2-PYRIDYLACETIC ACID DERIVATIVE, PREPARATION PROCESS THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4738977-A | 2-pyridylacetic acid derivatives, pharmaceutical composition containing the same and their use in treating ulcers | SUNTORY LIMITED (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0223512-A2 | 2-Pyridylacetic acid derivative, preparation process thereof and pharmaceutical composition containing the same | SUNTORY LIMITED (JP) | 1987-05-27 | — | — | EP | disclosed |