Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703145 | 0.89 | SMN1; SMN2 (0.54) | SMN1; SMN2MEN1GAAKMT2AMMP8 | |
| SCHEMBL9702660 | 0.86 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1GAAKMT2AMMP8 | |
| SCHEMBL9702863 | 0.86 | CASP1 (0.43) | SMN1; SMN2MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL9702851 | 0.86 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1GAAKMT2AMMP8 | |
| SCHEMBL1162993 | 0.85 | SMN1; SMN2 (0.66) | SMN1; SMN2MEN1GAAKMT2AMMP8 | |
| Hydrochloric Acid SCHEMBL10519969 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2MEN1GAAKMT2ANPC1 | |
| SCHEMBL9703922 | 0.84 | MEN1 (0.49) | SMN1; SMN2MEN1GAAKMT2AMMP8 | |
| SCHEMBL9703979 | 0.84 | MEN1 (0.38) | SMN1; SMN2MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL10337894 | 0.84 | SMN1; SMN2 (0.39) | SMN1; SMN2MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL9702695 | 0.84 | ALDH1A1 (0.49) | SMN1; SMN2MEN1GAAKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738977-A | 2-pyridylacetic acid derivatives, pharmaceutical composition containing the same and their use in treating ulcers | SUNTORY LIMITED (JP) | 1988-04-19 | — | — | US | claimed |
| JP-62108863-A | — | — | None | — | — | JP | disclosed |
| EP-0223512-B1 | 2-PYRIDYLACETIC ACID DERIVATIVE, PREPARATION PROCESS THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4738977-A | 2-pyridylacetic acid derivatives, pharmaceutical composition containing the same and their use in treating ulcers | SUNTORY LIMITED (JP) | 1988-04-19 | — | — | US | disclosed |
| JP-S62108863-A | 2-PYRIDYLACETIC DERIVATIVE, ITS PREPARATION AND MEDICINE CONTAINING THE SAME | SUNTORY LTD | 1987-05-20 | — | — | JP | disclosed |