Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.59 |
| ▸ | DRD4 | P21917 | 4/20 | 0.59 |
| ▸ | DRD3 | P35462 | 4/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028389 | 0.89 | CNR2 (0.50) | ALDH1A1FKBP1ACNR2CYP1A2CYP3A4 | |
| SCHEMBL2310681 | 0.88 | FKBP1A (0.51) | ALDH1A1FKBP1AMEN1KMT2ACNR2 | |
| SCHEMBL8484841 | 0.86 | FKBP1A (0.50) | ALDH1A1FKBP1ACNR2CYP1A2CYP3A4 | |
| SCHEMBL7459364 | 0.86 | FKBP1A (0.50) | ALDH1A1FKBP1ACNR2CYP1A2CYP3A4 | |
| SCHEMBL8484444 | 0.86 | FKBP1A (0.50) | ALDH1A1FKBP1ACNR2CYP1A2CYP3A4 | |
| SCHEMBL8483547 | 0.86 | FKBP1A (0.50) | ALDH1A1FKBP1ACNR2CYP1A2CYP3A4 | |
| SCHEMBL10375119 | 0.86 | FKBP1A (0.50) | ALDH1A1FKBP1ACNR2CYP1A2CYP3A4 | |
| SCHEMBL6586284 | 0.86 | FKBP1A (0.50) | ALDH1A1FKBP1ACNR2CYP1A2CYP3A4 | |
| SCHEMBL8483790 | 0.86 | FKBP1A (0.50) | ALDH1A1FKBP1ACNR2CYP1A2CYP3A4 | |
| SCHEMBL241683 | 0.83 | CA9 (0.54) | ALDH1A1FKBP1ACNR2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086051-A | 1H, 3H-pyrrolo[1,2-c]thiazole-7-carboxamide derivatives and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1992-02-04 | — | — | US | disclosed |