Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | HTR2B | P41595 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL734917 | 0.84 | HTR2C (0.79) | HTR2CADRB2KDM4EBRD4ALDH1A1 | |
| SCHEMBL13801324 | 0.78 | KDM4E (0.64) | HTR2CADRB2KDM4EBRD4ALDH1A1 | |
| SCHEMBL28594057 | 0.77 | HTR2C (0.74) | HTR2CADRB2KDM4EBRD4ALDH1A1 | |
| SCHEMBL807343 | 0.77 | HTR2C (0.74) | HTR2CADRB2KDM4EBRD4ALDH1A1 | |
| SCHEMBL27779740 | 0.76 | HTR2C (0.68) | HTR2CADRB2KDM4EBRD4ALDH1A1 | |
| SCHEMBL27468083 | 0.76 | HTR2C (0.68) | HTR2CADRB2KDM4EBRD4ALDH1A1 | |
| Tert-Butyl Formate SCHEMBL28799577 | 0.76 | HTR2C (0.70) | HTR2CADRB2KDM4EBRD4ALDH1A1 | |
| SCHEMBL2910862 | 0.76 | HTR2C (0.72) | HTR2CADRB2KDM4EBRD4ALDH1A1 | |
| SCHEMBL628780 | 0.75 | HTR2C (0.66) | HTR2CADRB2KDM4EBRD4ALDH1A1 | |
| SCHEMBL9703341 | 0.75 | HTR2C (0.60) | HTR2CADRB2KDM4EBRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012977-A1 | SUBSTITUTED INDOLES AS CENTRAL NERVOUS SYSTEM AGENTS | WARNER-LAMBERT COMPANY (US) | 1992-08-06 | — | — | WO | disclosed |
| US-5124332-A | Dopaminergic agents, hypotensive agents | WARNER-LAMBERT COMPANY (US) | 1992-06-23 | — | — | US | disclosed |