Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702177 | 0.85 | MAPK8 (0.44) | LMNASMN1; SMN2RECQLMAPK8MAPK9 | |
| SCHEMBL8999286 | 0.81 | L3MBTL1 (0.46) | LMNASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL28232823 | 0.80 | PLK1 (0.53) | MAPK8MAPK9MAPK10ATMHDAC8 | |
| SCHEMBL1338804 | 0.80 | PLK1 (0.53) | MAPK8MAPK9MAPK10ATMHDAC8 | |
| SCHEMBL8179369 | 0.77 | HPGD (0.49) | LMNAMAPK8MAPK9MAPK10ATM | |
| SCHEMBL9701736 | 0.77 | KDM4E (0.42) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9702198 | 0.76 | PPARG (0.42) | LMNAMEN1KMT2A | |
| SCHEMBL9267454 | 0.73 | HDAC3 (0.42) | LMNAMAPK8MAPK9MAPK10HDAC3 | |
| SCHEMBL6156562 | 0.73 | ALDH1A1 (0.43) | LMNASMN1; SMN2ATMMEN1KMT2A | |
| SCHEMBL5669568 | 0.73 | ALDH1A1 (0.43) | LMNASMN1; SMN2ATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2229151-A | — | — | None | — | — | JP | disclosed |
| US-5118710-A | SULFUR-CONTAINING ACRYLIC ESTERS AND FUNGICIDES CONTAINING THEM | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| JP-H02229151-A | SULFUR-CONTAINING ACRYLIC ESTER AND CONTROL OF FUNGI | BASF AG | 1990-09-11 | — | — | JP | disclosed |