Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 10/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PI4KA | P42356 | 2/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21999215 | 1.00 | AHCY (0.67) | AHCYADORA2AADORA1ALDH1A1PI4KA | |
| SCHEMBL23547672 | 0.89 | ADORA2A (0.60) | AHCYADORA2AADORA1ALDH1A1PI4KA | |
| SCHEMBL22855519 | 0.89 | ADORA2A (0.60) | AHCYADORA2AADORA1ALDH1A1PI4KA | |
| SCHEMBL22142773 | 0.87 | ADORA2A (0.66) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL17804432 | 0.87 | ADORA2A (0.66) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL2152705 | 0.85 | ADORA2A (0.64) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL13170083 | 0.85 | AHCY (0.61) | AHCYADORA2AADORA1ALDH1A1PI4KA | |
| SCHEMBL22448462 | 0.84 | AHCY (0.67) | AHCYADORA2AADORA1ALDH1A1PI4KA | |
| SCHEMBL99603 | 0.84 | AHCY (0.64) | AHCYADORA2AADORA1ALDH1A1PI4KA | |
| SCHEMBL6363452 | 0.84 | AHCY (0.64) | AHCYADORA2AADORA1ALDH1A1PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206459-B1 | 9-(PHOSPHONYLMETHOXYALKYL) ADENINES, METHOD FOR THEIR PREPARATION AND THEIR USE | Ceskoslovenska akademie ved (CS) | 1992-07-15 | — | — | EP | disclosed |
| US-4808716-A | VIRICIDES OR CHEMICAL INTERMEDIATES | CESKOSLOVENSKA AKADEMIC VED (CS) | 1989-02-28 | — | — | US | disclosed |
| EP-0206459-A2 | 9-(Phosphonylmethoxyalkyl) adenines, method for their preparation and their use | Ceskoslovenska akademie ved (CS) | 1986-12-30 | — | — | EP | disclosed |