Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.66 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.58 |
| ▸ | AHCY | P23526 | 7/20 | 0.56 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.54 |
| ▸ | PI4KA | P42356 | 2/20 | 0.54 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.54 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.54 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22142773 | 1.00 | ADORA2A (0.66) | ADORA2AADORA1ADORA2BAHCYNSD3 | |
| SCHEMBL2152705 | 0.93 | ADORA2A (0.64) | ADORA2AADORA1ADORA2BAHCYNSD3 | |
| SCHEMBL21999215 | 0.87 | AHCY (0.67) | ADORA2AADORA1ADORA2BAHCYPI4KA | |
| SCHEMBL9703479 | 0.87 | AHCY (0.67) | ADORA2AADORA1ADORA2BAHCYPI4KA | |
| SCHEMBL22460236 | 0.86 | ADORA2A (0.57) | ADORA2AADORA1ADORA2BNSD3PI4KA | |
| SCHEMBL20621738 | 0.85 | ADORA2A (0.56) | ADORA2AADORA1ADORA2BNSD3PI4KA | |
| SCHEMBL985053 | 0.83 | ADORA2A (0.57) | ADORA2AADORA1ADORA2BAHCYNSD3 | |
| SCHEMBL986231 | 0.83 | ADORA2A (0.56) | ADORA2AADORA1ADORA2BAHCYNSD3 | |
| SCHEMBL4088282 | 0.82 | ADORA2A (0.70) | ADORA2AADORA1ADORA2BAHCYPI4KA | |
| SCHEMBL22193338 | 0.82 | ADORA2A (0.69) | ADORA2AADORA1ADORA2BAHCYNSD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3028707-A1 | METHODS FOR TREATING OR PREVENTING OPHTHALMOLOGICAL DISEASES | Ophthotech Corporation (US) | 2016-06-08 | — | — | EP | disclosed |