Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 7/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9379210 | 0.75 | NPC1 (0.55) | PDE3BPDE3ANPC1RAB9AKDM4E | |
| SCHEMBL9385441 | 0.73 | NPC1 (0.53) | PDE3BPDE3ANPC1RAB9AKDM4E | |
| SCHEMBL10477969 | 0.73 | PDE4A (0.51) | PDGFRBFGFR1KDRAMY1APDE3B | |
| SCHEMBL10700314 | 0.73 | AMY1A (0.48) | PDGFRBFGFR1KDRAMY1APDE3B | |
| SCHEMBL10917045 | 0.71 | AMY1A (0.33) | AMY1AMETAP1KDM4E | |
| Hydrochloric Acid SCHEMBL10743666 | 0.70 | AMY1A (0.33) | AMY1AMETAP1KDM4E | |
| SCHEMBL9703307 | 0.70 | PDE4A (0.34) | PDGFRBFGFR1KDRAMY1APDE3B | |
| SCHEMBL9703617 | 0.69 | AMY1A (0.42) | AMY1APDE3BPDE3ANPC1RAB9A | |
| SCHEMBL9703323 | 0.69 | CDK4 (0.47) | AMY1APDE3BPDE3A | |
| SCHEMBL10576345 | 0.69 | SCN10A (0.38) | FGFR1KDRNPC1RAB9ALCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116843-A | Anticoagulants, hypotensive agents and cardiovascular disorder | BOEHRINGER MANNHEIM GMBH (DE) | 1992-05-26 | — | — | US | disclosed |