SCHEMBL9703661

SCHEMBL9703661

CCOC(=O)c1c(C(F)(F)F)nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c1C(F)(F)F

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRB3 P28472 12/20 0.61
GABRA2 P47869 7/20 0.61
GABRB2 P47870 7/20 0.61
GABRP O00591 3/20 0.61
GABRD O14764 3/20 0.61
GABRA1 P14867 3/20 0.61
GABRB1 P18505 3/20 0.61
GABRG2 P18507 3/20 0.61
GABRA5 P31644 3/20 0.61
GABRA3 P34903 3/20 0.61
GABRA4 P48169 3/20 0.61
GABRE P78334 3/20 0.61
GABRA6 Q16445 3/20 0.61
GABRG1 Q8N1C3 3/20 0.61
GABRG3 Q99928 3/20 0.61
GABRQ Q9UN88 3/20 0.61
ALDH1A1 P00352 1/20 0.42
RECQL P46063 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10571736 0.88 GABRB3 (0.76) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL10576102 0.82 GABRB3 (0.55) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL10574706 0.81 GABRP (0.53) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL10482885 0.80 GABRP (0.64) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL7711694 0.80 GABRB3 (0.77) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL7707130 0.80 GABRB3 (0.77) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL7706572 0.80 GABRB3 (0.77) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL10557794 0.79 GABRB3 (0.66) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL9704304 0.79 GABRB3 (0.76) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL10574120 0.78 KDM4E (0.37) GABRB3GABRA2GABRB2GABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992013451-A1 IMIDAZOLE PESTICIDES SCHERING AGROCHEMICALS LIMITED (GB) 1992-08-20 WO disclosed
US-4868198-A ARTHROPODICIDES BAYER AKTIENGESELLSCHAFT (DE) 1989-09-19 US disclosed
EP-0285947-A2 3-Haloalkyl-1-aryl-pyrazoles BAYER AG (DE) 1988-10-12 EP disclosed