SCHEMBL9703677

SCHEMBL9703677

CCCCCCCCOC(=O)c1ccc2cc(C(=O)O)ccc2c1Cl

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
ALDH1A1 P00352 3/20 0.50
LMNA P02545 1/20 0.50
TP53 P04637 2/20 0.48
CYP3A4 P08684 1/20 0.48
MAPK1 P28482 1/20 0.48
NPC1 O15118 1/20 0.47
MAPT P10636 1/20 0.47
RAB9A P51151 1/20 0.47
KDM4E B2RXH2 1/20 0.45
POLB P06746 1/20 0.45
HSD17B10 Q99714 1/20 0.45
PLA2G4B P0C869 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9222496 1.00 TSHR (0.50) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL3922392 0.82 ESR1 (0.49) TSHRLMNATP53CYP3A4MAPK1
SCHEMBL5360481 0.81 ALDH1A1 (0.56) TSHRALDH1A1TP53PLA2G4B
SCHEMBL28107934 0.81 ALDH1A1 (0.73) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL829039 0.81 TSHR (0.67) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL7078308 0.81 TSHR (0.67) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL17967704 0.81 TSHR (0.67) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL828217 0.81 TSHR (0.67) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL829228 0.81 TSHR (0.67) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL828469 0.81 TSHR (0.67) TSHRALDH1A1LMNATP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0465344-A1 Liquid crystal compounds Showa Shell Sekiyu Kabushiki Kaisha (JP) 1992-01-08 EP disclosed