SCHEMBL5360481

SCHEMBL5360481

CCCCCCCOc1ccc2cc(C(=O)O)ccc2c1Cl

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
HPGD P15428 1/20 0.56
PTPN11 Q06124 2/20 0.55
TP53 P04637 1/20 0.52
TSHR P16473 1/20 0.52
PLA2G2D Q9UNK4 1/20 0.52
PLA2G4B P0C869 1/20 0.51
RARB P10826 3/20 0.49
PLA2G2A P14555 1/20 0.49
LTB4R Q15722 1/20 0.48
THRA P10827 1/20 0.48
THRB P10828 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5342413 0.96 ALDH1A1 (0.51) ALDH1A1HPGDPTPN11TP53TSHR
SCHEMBL5349658 0.92 KMT2A (0.47) ALDH1A1HPGDPTPN11TP53TSHR
SCHEMBL5348705 0.85 ALDH1A1 (0.56) ALDH1A1HPGDPTPN11TP53TSHR
SCHEMBL8214320 0.82 ALDH1A1 (0.55) ALDH1A1HPGDPTPN11TP53TSHR
SCHEMBL9222496 0.81 TSHR (0.50) ALDH1A1TP53TSHRPLA2G4B
SCHEMBL9703677 0.81 TSHR (0.50) ALDH1A1TP53TSHRPLA2G4B
SCHEMBL18682278 0.81 THRA (0.68) ALDH1A1HPGDPTPN11TP53TSHR
SCHEMBL11315317 0.81 THRA (0.68) ALDH1A1HPGDPTPN11TP53TSHR
SCHEMBL9306386 0.81 THRA (0.68) ALDH1A1HPGDPTPN11TP53TSHR
SCHEMBL5348150 0.81 THRA (0.68) ALDH1A1HPGDPTPN11TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7186448-B2 Composition and method for temporarily fixing solid JSR CORPORATION (JP) 2007-03-06 US disclosed
US-20060275939-A1 Composition and method for temporarily fixing solids JSR CORPORATION (JP) 2006-12-07 US disclosed
US-20060087007-A1 Wafer treating apparatus and method DAINIPPON SCREEN MFG. CO., LTD. 2006-04-27 US disclosed
EP-1522567-A1 COMPOSITION AND METHOD FOR TEMPORARILY FIXING SOLID JSR Corporation (JP) 2005-04-13 EP disclosed
US-20040185187-A1 Composition and method for temporarily fixing solid JSR CORPORATION (JP) 2004-09-23 US disclosed
US-4094606-A Xerographic system employing waveguide addressing and modulating apparatus XEROX CORPORATION (US) 1978-06-13 US disclosed
US-4077700-A Waveguide addressing and modulating method and apparatus XEROX CORPORATION (US) 1978-03-07 US disclosed
US-3989355-A Electro-optic display system XEROX CORPORATION (US) 1976-11-02 US disclosed