Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11713527 | 1.00 | FFAR3 (0.47) | FFAR3LCKFYNTDP1OR51E2 | |
| Acetic Acid SCHEMBL2833260 | 0.83 | — | — | |
| Acetic Acid SCHEMBL1409006 | 0.82 | — | — | |
| Propionic Acid SCHEMBL16774628 | 0.81 | FFAR3 (0.59) | FFAR3TDP1OR51E2HSD17B10ALDH1A1 | |
| Acetoacetic Acid SCHEMBL11505796 | 0.81 | KDM4E (0.41) | FFAR3TDP1OR51E2TGFBR1LMNA | |
| SCHEMBL229980 | 0.78 | — | — | |
| Urea SCHEMBL133649 | 0.76 | TDP1 (0.43) | TDP1OR51E2LMNAHSD17B10ALDH1A1 | |
| Methacrylic Acid SCHEMBL3779015 | 0.76 | TDP1 (0.44) | FFAR3LCKFYNTDP1OR51E2 | |
| Methacrylic Acid SCHEMBL148580 | 0.76 | TDP1 (0.44) | FFAR3LCKFYNTDP1OR51E2 | |
| Methacrylic Acid SCHEMBL8424558 | 0.75 | FFAR3 (0.41) | FFAR3LCKFYNTDP1OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3466683-B1 | LAMINATED BODY, MULTI-LAYERED STRUCTURE, AND PRODUCTION METHODS THEREFOR | KURARAY CO (JP) | 2022-05-11 | — | — | EP | disclosed |
| US-11020942-B2 | Laminate, multilayered structure, and method for producing the same | KURARAY CO., LTD. (JP) | 2021-06-01 | — | — | US | disclosed |
| US-20200316920-A1 | LAMINATE, MULTILAYERED STRUCTURE, AND METHOD FOR PRODUCING THE SAME | KURARAY CO., LTD. (JP) | 2020-10-08 | — | — | US | disclosed |
| EP-3466683-A1 | LAMINATED BODY, MULTI-LAYERED STRUCTURE, AND PRODUCTION METHODS THEREFOR | Kuraray Co., Ltd. (JP) | 2019-04-10 | — | — | EP | disclosed |
| WO-2014016491-A1 | SYNTHESISING OF METHYL PROPANEDIOL FROM ALLYL ALCOHOL | ARKEMA FRANCE (FR) | 2014-01-30 | — | — | WO | disclosed |
| EP-0230018-B1 | PYRETHROIDE, PROCESS FOR THEIR PREPARATION AND THEIR USE IN COMBATTING PARASITES AS WELL AS PRECURSORS FOR THE PREPARATION OF THESE PYRETHROIDS | BASF Aktiengesellschaft (DE) | 1992-08-26 | — | — | EP | disclosed |