Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | BLM | P54132 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | PPARA | Q07869 | 2/20 | 0.60 |
| ▸ | F2 | P00734 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | PPARD | Q03181 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2636983 | 0.95 | PPARA (0.60) | MAPTMEN1KMT2AGAABLM | |
| SCHEMBL9703808 | 0.85 | EGFR (0.59) | MAPTMEN1KMT2AGAABCHE | |
| SCHEMBL30437396 | 0.82 | NPC1 (0.65) | MAPTMEN1KMT2AGAATP53 | |
| SCHEMBL11838896 | 0.81 | MAPT (0.84) | MAPTMEN1KMT2AGAABLM | |
| SCHEMBL24124340 | 0.81 | F2 (0.68) | MAPTMEN1KMT2AGAABLM | |
| SCHEMBL4095421 | 0.81 | PDGFRB (0.62) | MAPTMEN1KMT2AGAABLM | |
| SCHEMBL8082984 | 0.80 | MAPT (0.82) | MAPTMEN1KMT2AGAABLM | |
| SCHEMBL1680834 | 0.79 | NPC1 (0.65) | MAPTMEN1KMT2AGAABLM | |
| SCHEMBL12310114 | 0.78 | MAPT (0.66) | MAPTMEN1KMT2AGAABLM | |
| SCHEMBL24743620 | 0.78 | PPARA (0.69) | MAPTMEN1KMT2AGAABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221677-B1 | P-AMINOPHENOLS, DERIVATIVES THEREOF AND USE FOR MANUFACTURE OF A MEDICAMENT | E.R. Squibb & Sons, Inc. (US) | 1992-09-09 | — | — | EP | disclosed |
| US-4910208-A | Skin disorders, antiinflammatory agent | E. R. SQUIBB & SONS, INC. (US) | 1990-03-20 | — | — | US | disclosed |
| US-4814454-A | ANTIALLERGENS, ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1989-03-21 | — | — | US | disclosed |
| EP-0221677-A2 | p-Aminophenols, derivatives thereof and use for manufacture of a medicament | E.R. Squibb & Sons, Inc. (US) | 1987-05-13 | — | — | EP | disclosed |