Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.84 |
| ▸ | MEN1 | O00255 | 3/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.84 |
| ▸ | GAA | P10253 | 2/20 | 0.84 |
| ▸ | BLM | P54132 | 2/20 | 0.84 |
| ▸ | TP53 | P04637 | 1/20 | 0.84 |
| ▸ | ATM | Q13315 | 1/20 | 0.84 |
| ▸ | F2 | P00734 | 1/20 | 0.77 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.71 |
| ▸ | BCHE | P06276 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8082984 | 0.95 | MAPT (0.82) | MAPTMEN1KMT2AGAABLM | |
| SCHEMBL4667164 | 0.92 | MAPT (1.00) | MAPTMEN1KMT2AGAABLM | |
| SCHEMBL3720530 | 0.91 | MEN1 (0.76) | MAPTMEN1KMT2AGAABLM | |
| SCHEMBL15458727 | 0.89 | MAPT (0.73) | MAPTMEN1KMT2AGAABLM | |
| SCHEMBL6806474 | 0.88 | MAPT (0.72) | MAPTMEN1KMT2AGAABLM | |
| SCHEMBL7316316 | 0.87 | F2 (1.00) | MAPTMEN1KMT2AGAABLM | |
| SCHEMBL1844630 | 0.87 | MAPT (0.70) | MAPTMEN1KMT2AGAABLM | |
| SCHEMBL11253865 | 0.87 | MAPT (0.74) | MAPTMEN1KMT2AGAABLM | |
| SCHEMBL17609148 | 0.85 | MEN1 (0.68) | MAPTMEN1KMT2AGAABLM | |
| SCHEMBL17602106 | 0.84 | MAPT (0.71) | MAPTMEN1KMT2AGAABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104013630-B | A kind of compound bazedoxifene acetate estrogen compositions | 合肥九研医药科技开发有限公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-103739540-B | A kind of preparation method of bazedoxifene acetate intermediate | CHINA RESOURCES SAIKE PHARMACEUTICAL CO., LTD. (CN) | 2016-05-04 | — | — | CN | disclosed |
| CN-103739540-B | A kind of preparation method of bazedoxifene acetate intermediate | CHINA RESOURCES SAIKE PHARMACEUTICAL CO., LTD. (CN) | 2016-05-04 | — | — | CN | disclosed |
| CN-104013630-A | Compound bazedoxifene acetate estrogen composition | HEFEI JIUYAN MEDICINE TECHNOLOGY DEV CO LTD | 2014-09-03 | — | — | CN | disclosed |
| CN-103739540-A | Method for preparing bazedoxifene acetate intermediate | CHINA RESOURCES SAIKE PHARMACEUTICAL CO LTD | 2014-04-23 | — | — | CN | disclosed |
| US-3948939-A | 9-Acyl-1,2,3,4-tetrahydrocarbazole-3 and 4-carboxylic acids | STERLING DRUG INC. (US) | 1976-04-06 | — | — | US | disclosed |