Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703966 | 0.91 | HPGD (0.44) | DYRK1AHPGDKMT2AALDH1A1POLB | |
| SCHEMBL9704640 | 0.90 | KMT2A (0.45) | HPGDKMT2AALDH1A1POLBMEN1 | |
| SCHEMBL9704612 | 0.90 | KDM4E (0.42) | HPGDKMT2AALDH1A1POLBADRB2 | |
| SCHEMBL9703371 | 0.87 | KDM4E (0.43) | HPGDALDH1A1POLBLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL9703676 | 0.86 | KDM4E (0.42) | HPGDALDH1A1POLBLMNAKDM4E | |
| SCHEMBL9703766 | 0.86 | HPGD (0.37) | HPGDKMT2AALDH1A1POLBADRB2 | |
| SCHEMBL9703318 | 0.84 | PLAT (0.35) | DYRK1AHPGDKMT2AALDH1A1POLB | |
| SCHEMBL9704661 | 0.81 | DYRK1A (0.39) | DYRK1AHPGDKMT2AALDH1A1POLB | |
| SCHEMBL9703387 | 0.80 | MEN1 (0.51) | HPGDKMT2AALDH1A1POLBADRB2 | |
| SCHEMBL9704563 | 0.79 | ALDH1A1 (0.42) | HPGDALDH1A1POLBLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203795-B1 | Benzo [i,j] quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and process for preparing the same | TOKYO TANABE COMPANY LIMITED (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4720495-A | Benzo[ij]quinolizine-2-carboxylic acids useful for treating bacterial infection | TOKYO TANABE CO. LIMITED (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0203795-A2 | Benzo [i,j] quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and process for preparing the same | TOKYO TANABE COMPANY LIMITED (JP) | 1986-12-03 | — | — | EP | disclosed |